Focus on Birth Defects Research

This chapter shows new research which aim to overcome the limits in percutaneous treatment of congenital heart defect . ... Introduction Atrial septal defect ( ASD ) and ventricular septal In : Focus on Birth Defects Research ISBN ...

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Author: Janet V. Engels

Publisher: Nova Publishers

ISBN: 1594549591

Category: Medical

Page: 243

View: 620

Birth defects are defined as abnormalities of structure, function, or body metabolism that are present at birth. These abnormalities lead to mental or physical disabilities or are fatal. There are more than 4,000 different known birth defects ranging from minor to serious, and although many of them can be treated or cured, they are the leading cause of death in the first year of life. This book presents leading research in this field from around the world.

Birth Defects

FEDERALLY SPONSORED BIRTH DEFECTS RESEARCH AND SERVICES Although we at the March of Dimes are justifiably proud of ... for two recent legislative initiatives that focus on birth defects prevention : the Birth Defects Prevention Act of ...

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Author: United States. Congress. Senate. Committee on Health, Education, Labor, and Pensions. Subcommittee on Children and Families

Publisher:

ISBN: UOM:39015090408264

Category: Abnormalities, Human

Page: 48

View: 443

Folate in Health and Disease

During the fifteen years since the bestselling first edition of Folate in Health and Disease was published, there have been thousands of new research studies related to folate and its role in health and disease.

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Author: Lynn B. Bailey

Publisher: CRC Press

ISBN: 9781420071252

Category: Medical

Page: 602

View: 946

During the fifteen years since the bestselling first edition of Folate in Health and Disease was published, there have been thousands of new research studies related to folate and its role in health and disease. The second edition of the book uniquely bridges the gap between basic science and public health/clinical medicine.Presents Groundbreaking

March of Dimes

In 1964 , the foundation phased out the arthritis component and focused on birth defects , helping to create more than 100 birth defects research and treatment centers across the United States by 1968. Dr. Virginia Apgar , most widely ...

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Author: David W. Rose

Publisher: Arcadia Publishing

ISBN: 0738512532

Category: History

Page: 128

View: 982

For more than half a century, a deadly viral disease known as poliomyelitis, or infantile paralysis, caused permanent crippling injury to thousands of Americans. Many died from polio; others were disabled for life. Summertime epidemics brought fear to anxious parents who tried to protect their children during "polio season." Although a cure was never found, protection came in the form of a vaccine developed by Dr. Jonas Salk, a grantee of the National Foundation for Infantile Paralysis. The foundation, better known as the March of Dimes, succeeded in its efforts to eradicate polio from the United States and expanded its mission to the prevention of birth defects and infant mortality. March of Dimes documents one of the most successful voluntary health organizations in history. Founded by Pres. Franklin Delano Roosevelt in 1938, the March of Dimes thrives on the dedication and energy of volunteers. American celebrities from Eddie Cantor to Helen Hayes and Elvis Presley have joined the fight against polio and birth defects. Millions participate in WalkAmerica, the nation's best-known walkathon fund-raiser, and March of Dimes poster children have symbolized the challenge of life with crippling diseases. Unlike any other, the March of Dimes story is an astonishing blend of science, medicine, and American popular culture.

Focus on Down s Syndrome Research

Breakthroughs in genetic engineering offer new hope for this field. This book offers state-of- the art reports on efforts to better understand and push forward this dynamic field of medical research.

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Author: Jeffrey A. Malard

Publisher: Nova Science Pub Incorporated

ISBN: 1590338936

Category: Medical

Page: 241

View: 643

Down's Syndrome is a chromosome abnormality, usually due to an extra copy of the 21st chromosome, although not invariably, resulting in mental retardation and other abnormalities. It is the most common single cause of birth defects with an incidence of 1 in 660 births. Children with Down syndrome have a widely recognised characteristic appearance. The head may be smaller than normal and abnormally shaped. Prominent facial features include a flattened nose, protruding tongue, and upward slanting eyes. Retardation of normal growth and development is typical and most affected children never reach average adult height. Congenital heart defects are frequently present in these infants as are other medical difficulties. Breakthroughs in genetic engineering offer new hope for this field. This book offers state-of- the art reports on efforts to better understand and push forward this dynamic field of medical research.

Focus on Mental Retardation Research

One common criterion for diagnosis of mental retardation is a tested intelligence quotient (IQ) of 70 or below. This book examines new and critical research and issues in the field.

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Author: Marina I. Carson

Publisher: Nova Publishers

ISBN: 1600216471

Category: Medical

Page: 226

View: 403

Mental retardation is a term for a pattern of persistently slow learning of basic motor and language skills ("milestones") during childhood, and a significantly below-normal global intellectual capacity as an adult. One common criterion for diagnosis of mental retardation is a tested intelligence quotient (IQ) of 70 or below. This book examines new and critical research and issues in the field.

Pharmacoepidemiology

HOPE FOR AN INTEGRATED APPROACH Studies of birth defects in the future will undoubtedly focus increased attention on issues of statistical power, validity, and secular changes in exposures. The continuing concern about isotretinoin and ...

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Author: Brian L. Strom

Publisher: John Wiley & Sons

ISBN: 9780470866832

Category: Medical

Page: 910

View: 278

The fourth edition of Pharmacoepidemiology is an outstanding and fully comprehensive textbook, which will be an essential resource for all interested in the field—in academia, in regulatory agencies, in industry and in the law. Brian Strom’s classic textbook continues both to reflect the increased maturation of pharmacoepedemiology and to help shape it’s direction. Reviews of previous editions of his celebrated textbook include: "The book is essential reading for anyone interested in pharmacoepidemiology." INTERNATIONAL JOURNAL OF EPIDEMIOLOGY “...an excellent textbook and a comprehensive reference which belongs in the library of every pharmaceutical manufacturer and regulator." EUROPEAN JOURNAL OF PUBLIC HEALTH

Environmental Health Perspectives

Combined with the RO1s funded under the first initiative , these projects expanded the network of researchers focused on the study of structural birth defects . By issuing this PA , " Developmental Mechanisms of Human Structural Birth ...

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Author:

Publisher:

ISBN: MINN:30000010711475

Category: Environmental health

Page:

View: 172

Stem Cells in Birth Defects Research and Developmental Toxicology

Research on alcohol's neurotoxicological and neuroteratological effects in Fetal Alcohol Spectrum Disorders (the CNS, ... The region examined is also important, but the vast majority of studies in the AUD field have focused on the ...

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Author: Theodore P. Rasmussen

Publisher: John Wiley & Sons

ISBN: 9781119283225

Category: Science

Page: 368

View: 860

This book contains material contributed by forward-looking scientists who work at the interface of stem cell research and applied science with the aim to improve human fetal safety and the understanding of human developmental and degenerative disorders. Provides important platforms and contemporary accounts of the state of stem cell research in the fields of toxicology and teratology Considers both in vitro uses of stem cells as platforms for teratology and also stem cellopathies, which are in vivo developmental and degenerative disorders Helps the pharmaceutical industry and safety and environmental authorities validate the status quo of in vitro toxicity test systems based on human pluripotent stem cells and their derivatives

Birth Defects Surveillance

This manual is a collaborative effort between the World Health Organization (WHO), the National Center on Birth Defects and Developmental Disabilities from the US Centers for Disease Control and Prevention (CDC) and the International ...

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Author: World Health Organization

Publisher:

ISBN: 924154872X

Category: Medical

Page: 122

View: 500

Birth Defects Surveillance: A Manual for Programme Managers was highly commended in the Public Health category of the British Medical Association 2015 Medical Book Competition. Congenital anomalies, also known as birth defects, are structural or functional abnormalities, including metabolic disorders, which are present from birth. Congenital anomalies are a diverse group of disorders of prenatal origin, which can be caused by single gene defects, chromosomal disorders, multifactorial inheritance, environmental teratogens or micronutrient deficiencies. This manual is intended to serve as a tool for the development, implementation and ongoing improvement of a congenital anomalies surveillance program, particularly for countries with limited resources. The focus of the manual is on population-based and hospital-based surveillance programs. Some countries may not find it feasible to begin with the development of a population-based program. Therefore, the manual focuses on the methodology needed for the development of both population-based and hospital-based surveillance program. Further, although many births in predominantly low- and middle-income countries occur outside of hospitals, some countries with limited resources may choose to start with a hospital-based surveillance program and expand it later into one that is population based. Any country wishing to expand its current hospital-based program into a population-based program, or to begin the initial development of a population-based registry, should find this manual helpful in reaching its goal. This manual provides selected examples of congenital anomalies. Typically, these anomalies are severe enough that they would probably be captured during the first few days following birth. Also, because of their severity and frequency, these selected conditions have significant public health impact, and for some there is a potential for primary prevention. Nevertheless, these are just suggestions, and countries can choose to monitor a subset of these conditions or add other congenital anomalies to meet their needs. This manual is a collaborative effort between the World Health Organization (WHO), the National Center on Birth Defects and Developmental Disabilities from the US Centers for Disease Control and Prevention (CDC) and the International Clearinghouse for Birth Defects Surveillance and Research (ICBDSR).