Primary Immunodeficiency Diseases

This is the second edition of a practical reference textbook on PIDs that has been widely welcomed by scientists and clinicians from around the world.

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Author: Nima Rezaei

Publisher: Springer

ISBN: 9783662529096

Category: Medical

Page: 582

View: 362

The number of diagnosed cases of primary immunodeficiency diseases (PIDs) – a group of inborn disorders of the immune system – is growing rapidly, but misdiagnosis or late diagnosis still occurs in a significant number of patients, with serious consequences. This is the second edition of a practical reference textbook on PIDs that has been widely welcomed by scientists and clinicians from around the world. The new edition has been extensively revised to reflect advances in knowledge and includes various PIDs not previously covered. For each disease, information is provided on definition, etiology, clinical manifestations, diagnosis, and management. This book will represent an ideal resource for specialists when engaging in diagnosis, clinical decision-making, and treatment planning. It will also prove invaluable for doctors in training and other physicians and nurses who wish to learn more about PIDs.

Primary Immunodeficiency Diseases

This book will present the principles of immunology, genetics, and molecular biology as they pertain to the primary immunodeficiency diseases; the hallmark of these diseases is an increased susceptbility to infections.

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Author: Hans D. Ochs

Publisher: Oxford University Press, USA

ISBN: 9780195147742

Category: Medical

Page: 726

View: 632

The second edition of Primary Immunodeficiency Diseases presents discussions of gene identification, mutation detection, and clinical and research applications for over 100 genetic immune disorders--disorders featuring an increased susceptibility to infections and, in certain conditions, an icreased rate of malignancies and autoimmune disorders. Since the publication of the first edition, a flurry of new disease entities has been defined and new treatment regimens have been introduced, the most spectacular being successful treatment by gene therapy for two genotypes of combined immunodeficiency. The first edition marked a historic turning point in the field of immunodeficiencies, demonstrating that many of the disorders of the immune systam could be understood at a molecular level. This new edition can proudly document the tremendous pace of progress in dissecting the complex immunologic networks responsible for protecting individuals from these disorders.

Primary Immunodeficiency Diseases

This third edition of Primary Immunodeficiency Diseases provides readers with the historic and scientific background, clinical presentations, immunologic characteristics, and the molecular/genetic underpinnings of this rapidly enlarging ...

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Author: Hans D. Ochs, MD, Dr.med

Publisher: Oxford University Press

ISBN: 9780199971039

Category: Medical

Page: 800

View: 276

Primary immunodeficiency diseases, first recognized 60 years ago, are inherited disorders that affect human adaptive and innate immunity. In most cases, affected individuals experience recurrent infections, but they may also suffer from autoimmune diseases and malignancies. This third edition of Primary Immunodeficiency Diseases provides readers with the historic and scientific background, clinical presentations, immunologic characteristics, and the molecular/genetic underpinnings of this rapidly enlarging class of diseases. With up-to-date diagnostic tools and therapeutic options -- from prophylactic anti-infective measures to hematopoietic stem cell transplantation and gene therapy -- this volume will remain an authoritative resource on this increasingly important area.

Primary Immunodeficiency Disorders

This book provides an understanding of the process going from clinical problem to lab and back to the clinic, based on historical experiences.

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Author: Amos Etzioni

Publisher: Academic Press

ISBN: 9780124115545

Category: Medical

Page: 376

View: 454

Primary Immunodeficiency Disorders: A Historic and Scientific Perspective provides a complete historical context that is crucial for students and researchers concerned with primary immunodeficiency. When researchers have a poor understanding of the way we arrived where we are in research, they can miss important points about a disease, or miss out on how to approach new diseases. This historical knowledge of research can assist greatly by showing how it was done in the past, demonstrating the successes and failures, so that it can be done better in the future. This book provides an understanding of the process going from clinical problem to lab and back to the clinic, based on historical experiences. Its chapters proceed from the discovery of the T and B cell lineages through the first BMT for immunodeficiency disorder; lab investigation and gene therapy for PID; the discovery of the gene for AT and its function; understanding cytokine defects; and many other stops along the way. Facilitates communication among physicians and other investigators concerned with immunological and inflammatory diseases Summarizes for the first time all the known facts from 60 years of primary immunodeficiency research, and teaches how an important field in medicine was established Provides stimulating discussions on developing new medical therapies Highlights the importance of studying humans to understand mechanisms of disease that affect humans

Pulmonary Manifestations of Primary Immunodeficiency Diseases

This book provides a broad overview of the respiratory manifestations associated with Primary Immune deficiencies (PID) congenital genetic defects such as infections, chronic inflammation, autoimmunity, lymphoproliferation, allergic ...

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Author: Seyed Alireza Mahdaviani

Publisher: Springer

ISBN: 3030008797

Category: Medical

Page: 286

View: 271

This book provides a broad overview of the respiratory manifestations associated with Primary Immune deficiencies (PID) congenital genetic defects such as infections, chronic inflammation, autoimmunity, lymphoproliferation, allergic manifestations and rare forms of cancer. Since the most common site of involvement in PID is the lung, the pulmonologists (pediatrics or adult), Internists and General Practitioners may be among the first to recognize the pattern of pulmonary disorders, leading to diagnosis of PID. Pulmonary complications present a significant cause of morbidity and also mortality among patients suffering from different forms of PID. With the prevalence of lung infections and disease so high in PID patients, respiratory professionals will find this book to be an essential resource for diagnosing, managing and referring PID related pulmonary disorders in clinical practice.

Primary Immunodeficiency Disorders An Issue of Immunology and Allergy Clinics of North America 35 4

This issue of Immunology and Allergy Clinics of North America, Guest Edited by Anthony Montanaro, MD, is devoted to Primary Immunodeficiency Disorders.

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Author: Anthony Montanaro

Publisher: Elsevier Health Sciences

ISBN: 9780323413350

Category: Medical

Page: 778

View: 447

This issue of Immunology and Allergy Clinics of North America, Guest Edited by Anthony Montanaro, MD, is devoted to Primary Immunodeficiency Disorders. Dr. Montanaro has assembled a group of expert authors to review the following topics: Overview of Immunodeficiency Disorder; Severe Combined Immunodeficiency Disorder; Specific Antibody Deficiencies; Common Variable Immunodeficiency; Pulmonary Manifestations of Primary Immunodeficiency Disorders; Approach to the Child with Recurrent Infections; Immunoglobulin Treatment for Primary Immunodeficiency; Bone Marrow Transplantation for Primary Immunodeficiency; and Autoimmune Manifestations of Primary Immunodeficiency.

Clinical Cases in Primary Immunodeficiency Diseases

This book aims to increase the clinical awareness and knowledge of practicing clinicians regarding the diagnosis and management of PIDs.

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Author: Asghar Aghamohammadi

Publisher: Springer Science & Business Media

ISBN: 9783642317859

Category: Medical

Page: 380

View: 798

Primary immunodeficiency diseases (PIDs) are a heterogeneous group of inherited disorders characterized by different defects in the development and function of the immune system. This book aims to increase the clinical awareness and knowledge of practicing clinicians regarding the diagnosis and management of PIDs. In order to achieve this goal, about 90 cases drawn from real life are presented, along with approximately 300 related questions. The selected case reports are the result of the invaluable cooperation of more than 40 scientists in the field of immunodeficiency. They focus both on the presenting features of patients with PIDs and on the required further investigation and management. Each of the numbered cases is followed by the questions, their answers, and additional discussion. Each question focuses on a particular aspect of the PID under consideration, and the topics covered include clinical diagnosis, laboratory findings, molecular mechanisms, and therapy.

Primary Immunodeficiency Diseases

PRIMARY IMMUNODEFICIENCY DISEASES Report of a WHO Scientific Group *
1 . INTRODUCTION Immunity results from many complex interacting mechanisms
. The skin and mucous membranes are nonspecific barriers to infection .

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Author: Martha M. Eibl

Publisher:

ISBN: UCAL:B4495085

Category: Immunologic Deficiency Syndromes

Page: 378

View: 276

The Clinical Presentation of the Primary Immunodeficiency Diseases

IMMUNODEFICIENCY DIS E A SE S SELECTED EXAMPLES OF PRIMARY
IMMUNODEFICIENCY DISEASES COMBINED B- AND T - LYMPHOCYTE
DEFECTS Severe Combined Immunodeficiency Wiskott - Aldrich Syndrome
Ataxia ...

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Author:

Publisher:

ISBN: UOM:39015057619002

Category: Immunological deficiency syndromes

Page: 6

View: 310

Primary Immunodeficiency Disorders

Articles in this issue include: Personalized therapy: Immunoglobulin replacement for antibody deficiency; Newborn Screening for Severe Combined Immunodeficiency: Update on newborn screening and lessons learned; Update on Advances in ...

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Author: Lisa Kobrynski

Publisher: Elsevier Health Sciences

ISBN: 9780323654425

Category: Medical

Page:

View: 154

This issue of Immunology and Allergy Clinics of North America, Guest Edited by Dr. Lisa Kobrynski, is devoted to Primary Immune Deficiencies. Articles in this issue include: Personalized therapy: Immunoglobulin replacement for antibody deficiency; Newborn Screening for Severe Combined Immunodeficiency: Update on newborn screening and lessons learned; Update on Advances in Hematopoietic Cell Transplantation for Primary Immunodeficiency Disorders; Hereditary Autoinflammatory Disorders: Recognition and treatment of inflammatory disorders of the immune system; Use of Immunomodulatory Agents to Treat Primary Immune Deficiencies: Mechanism-based therapy; Secondary Hypogammaglobulinemia: An increasingly recognized complication of treatment with immunomodulators and post-solid organ transplantation; Use of Vaccines in Primary Immunodeficiency; Gastrointestinal Manifestations and Complications of Primary Immunodeficiency Disorders; Hyper IgE Syndromes; Early Onset Inflammatory Bowel Disease; and Genome Testing to Diagnose Primary Immunodeficiency Disorders and to Identify Targeted Therapy.

Screening for Primary Immunodeficiency Disorders PIDDs in Neonates

Topic Editor Prof. Lennart Hammarström holds equity in ImmunoIVD. All other Topic Editors declare no competing interests with regards to the Research Topic subject.

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Author: Elham Hossny

Publisher: Frontiers Media SA

ISBN: 9782889664542

Category: Medical

Page:

View: 412

Topic Editor Prof. Lennart Hammarström holds equity in ImmunoIVD. All other Topic Editors declare no competing interests with regards to the Research Topic subject.

Primary Immune Deficiency Diseases

what are the Primary Immunodeficiency Diseases ? Immunodeficiency diseases
result when any portion of this complex system is missing or does not function
properly . There are 3 main classes of immunodeficiency diseases that involve ...

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Author:

Publisher:

ISBN: UOM:39015069222910

Category:

Page:

View: 846

Departments of Labor Health and Human Services Education and Related Agencies Appropriations for 2002

78 ) Action taken or to be taken The NICHD supports and conducts basic , clinical
, and translational research on inherited or primary immunodeficiency diseases .
Moreover , the NICHD sponsors educational activities , conferences , symposia ...

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Author: United States. Congress. House. Committee on Appropriations. Subcommittee on the Departments of Labor, Health and Human Services, Education, and Related Agencies

Publisher:

ISBN: STANFORD:36105050220255

Category: United States

Page:

View: 898

Departments of Labor Health and Human Services Education and Related Agencies Appropriations for 2005

Primary Immunodeficiency Diseases Primary immunodeficiency diseases are
caused by intrinsic defects in the cells of ... This is in contrast to secondary
immunodeficiency diseases, which are due to another illness or infection, such
as HIV.

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Author: United States. Congress. House. Committee on Appropriations. Subcommittee on the Departments of Labor, Health and Human Services, Education, and Related Agencies

Publisher:

ISBN: MINN:31951D02570187S

Category: United States

Page:

View: 925

Departments of Labor Health and Human Services Education and Related Agencies Appropriations for 2007

Action taken or to be taken The NIAID is deeply committed to supporting research
efforts aimed at understanding the causes and immune mechanisms leading to
the development of primary immunodeficiency diseases . To this end , in FY ...

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Author: United States. Congress. House. Committee on Appropriations. Subcommittee on the Departments of Labor, Health and Human Services, Education, and Related Agencies

Publisher:

ISBN: MINN:31951D02598312Z

Category: United States

Page:

View: 483

The Nature Cellular and Biochemical Basis and Management of Immunodeficiencies

Introduction The primary immunodeficiency syndrome is a group of diseases
caused by defect of the factor related to the defense mechanism of the host , and
in most cases it is noticed because of recurrent infections . By examining the
clinical ...

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Author: Robert A. Good

Publisher: Wiley-Liss

ISBN: UOM:39015012583095

Category: Medical

Page: 647

View: 437

Recent Advances in Primary and Acquired Immunodeficiencies

However, since we are late, I wish to concentrate on primary immunodeficiency
diseases where it is obvious that recent progress and future avenues mainly
pertain at present to two fields, the membrane defects and the studies in
molecular ...

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Author: Fred S. Rosen

Publisher: Lippincott Williams & Wilkins

ISBN: UOM:39015012538776

Category: Medical

Page: 434

View: 598