Molecular Pathology

This book is a valuable resource for students, biomedical researchers, practicing physician-scientists who undertake disease-related basic science and translational research, and pathology residents and other postdoctoral fellows. * Exam ...

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Author: William B. Coleman

Publisher: Academic Press

ISBN: 0123859123

Category: Science

Page: 664

View: 273

Molecular Pathology: The Molecular Basis of Human Disease provides a current and comprehensive view of the molecular basis and mechanisms of human disease. Combining accepted principles with broader theoretical concepts and with contributions from a group of experts, the book looks into disease processes in the context of traditional pathology and their implications for translational molecular medicine. It also discusses concepts in molecular biology and genetics, recent scientific and technological advances in modern pathology, the concept of ""molecular pathogenesis"" of disease, and how disease evolves from normal cells and tissues due to perturbations in molecular pathways. The book describes the integration of molecular and cellular pathogenesis using a bioinformatics approach and a systems biology approach to disease pathogenesis. It also discusses current and future strategies in molecular diagnosis of human disease, and the impact of molecular diagnosis on treatment decisions and the practice of personalized medicine. This book is a valuable resource for students, biomedical researchers, practicing physician-scientists who undertake disease-related basic science and translational research, and pathology residents and other postdoctoral fellows. * Exam Master® web site will host "Self-assessment" questions that students can use to study for the molecular section of the board exam * Companion Web Site – will host a complete set of PowerPoint slides: to include images from the book and additional images for teaching; course materials; lecture materials * Teaches from the perspective of “integrative systems biology, which encompasses the intersection of all molecular aspects of biology, as applied to understanding human disease * Outlines the principles and practice of molecular pathology * Explains the practice of “molecular medicine and the translational aspects of molecular pathology

Basic Genetics

Basic Genetics is a concise introductory textbook that focuses not only on understanding and explaining the main points of genetics, but also upon covering the required essential traditional subjects in the field.

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Author: Ahmed Abouelmagd

Publisher: Universal-Publishers

ISBN: 9781612331928

Category: Science

Page: 288

View: 660

Basic Genetics is a concise introductory textbook that focuses not only on understanding and explaining the main points of genetics, but also upon covering the required essential traditional subjects in the field. The main goal of this textbook is to help first year students who are taking their first course in human genetics to understand the different topics within genetics. It is of particular interest for those who are preparing themselves to study medicine or other medical sciences. This textbook presents only the essential required information. Some of the different subjects included in the eight chapters are: cell cycle and cellular division, Mendelian principles of heredity, the molecular basis of genetic material, gene expression and gene expression control, genetic variations and genetic engineering, as well as human genetics. In addition, Basic Genetics contains multiple choice questions covering each topic and their answers. These questions are absolutely essential for students' self- assessment. These different topics of basic genetics have also been illustrated by simple diagrams in full color.

Human Molecular Genetics

However, all of the genes together are only a small part of DNA code. The 30,000 odd genes in human DNA might only make up 4% of human DNA. This book presents a view in depth of the principal aspects of life science.

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Author: Jamie Benton &

Publisher: Scientific e-Resources

ISBN: 9781839471629

Category:

Page: 336

View: 615

Molecular Genetics is one of the fast moving fields of science that has undergone a variable revolution over the last two decades leading to major advances in the understanding of gene structure and function at molecular level. Human Molecular Genetics is the study of the molecular basis of human genetic disease, developmental genetics, neurogenetics, chromosome structure and function, molecular aspects of cancer genetics, gene therapy, biochemical genetics, major advances in gene mapping and understanding of genome organization. Genetics is the study of how genes bring about characteristics, or traits, in living things and how those characteristics are inherited. Genes are portions of DNA molecules that determine characteristics of living things. Through the processes of meiosis and reproduction, genes are transmitted from one generation to the next. Heredity is a biological process where a parent passes certain genes onto their children or offspring. Genetics uses information from one or two genes to explain a disease or condition, whereas genomics examines all of the genetic information to determine biological markers predisposing an individual to disease. Genes are the best understood subsequence of DNA code. Most genes clearly encode the data sequence representing a particular protein. However, all of the genes together are only a small part of DNA code. The 30,000 odd genes in human DNA might only make up 4% of human DNA. This book presents a view in depth of the principal aspects of life science. Each chapter treats a discrete topic within the scope of biology and each is designed for students who are exposed to the topics for the first time. Since considerable ferment exists in the biological sciences today, it is increasingly important to keep pace with current developments.

Color Atlas of Genetics

Brief descriptions of numerous genetic diseases are included, with references for more detailed information.Readers will find that this incomparable book presents a comprehensive picture of the field from its fascinating history to its most ...

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Author: Eberhard Passarge

Publisher: Thieme

ISBN: 9781604061383

Category: Medical

Page: 496

View: 538

A remarkable achievement by a single author...concise but informative...No geneticist or physician interested in genetic diseases should be without a copy of this remarkable edition. --American Journal of Medical GeneticsMore than ever, a solid understanding of genetics is a fundamental element of all medical and scientific educational programs, across virtually all disciplines. And the applications--and implications--of genetic research are at the heart of current medical scientific debates. Completely updated and revised, The Color Atlas of Genetics is an invaluable guide for students of medicine and biology, clinicians, and anyone else interested in this rapidly evolving field. The latest edition of this highly praised atlas retains several popular features, such as the accessible layout and logical structure, in addition to many novel features and 20 completely new color plates on new topics, including: Cell-to-cell communication, including important signaling and metabolic pathways Taxonomy of living organisms (tree of life) Epigenetic modifications in chromatin Apoptosis RNA interference (RNAi) Comparative genomic hybridization Origins of cancer Principles of gene and stem cell therapy, etc. With more than 200 absorbing full-color plates concisely explained on facing pages, the atlas offers readers an easy-to-use, yet remarkably detailed guide to key molecular, theoretical, and medical aspects of genetics and genomics. Brief descriptions of numerous genetic diseases are included, with references for more detailed information.Readers will find that this incomparable book presents a comprehensive picture of the field from its fascinating history to its most advanced applications.

Vital Forces

The story is told in a clear, engaging, and absorbing manner. This delightful work relates the fascinating and staggering advances in concepts and theories over the last 200 years and introduces the major figures of the times.

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Author: Graeme K. Hunter

Publisher: Academic Press

ISBN: 0123618118

Category: Medical

Page: 364

View: 455

Combining science and biography into a seamless chronological narrative, the author of Vital Forces brings to life the successes and failures, collaborations and feuds, and errors and insights that produced the revolution in biology. The story is told in a clear, engaging, and absorbing manner. This delightful work relates the fascinating and staggering advances in concepts and theories over the last 200 years and introduces the major figures of the times. Vividly describes dramatic scientific discoveries, personalities, feuds and rivalries Answers a general readers quest to understand the nature of life, and the relevance of biochemistry/molecular biology to modern medicine, industry and agriculture

The Molecular Basis of Evolution

The omnivorous reader will find Nanney ' s review10 of the subject of cytoplasmic
heredity in The Chemical Basis of Heredity excellent reading The list of
omissions can be extended . The chemistry of RNA and its genetic properties ,
the ...

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Author: Christian B. Anfinsen

Publisher:

ISBN: UOM:39015006146818

Category: Evolution

Page: 228

View: 607

Research Awards Index

HL - 01263-20 Mechanisms of destruction of red cells ** AM - 13430-03
Research and heredity clinic ** AM - 15465-01 ... and hemoglobinopathies ** AM
- 13359-04 Molecular basis , genetics of glycogen storage genetic diagnosis (
human ) ...

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Author:

Publisher:

ISBN: STANFORD:36105119623762

Category: Medicine

Page:

View: 917

Cytology Genetics and Molecular Biology

CYTOLOGY 1.

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Author: P. K. Gupta

Publisher:

ISBN: 144167215X

Category: Cytology

Page: 664

View: 711

CYTOLOGY 1. Cell Theory and The Cell 2. Techniques for Cell Study 3. Cell Wall and Extracellular Matrix 4. Structure of Cell Membrane (Including Plasma Membrane) 5. Functions of Cell Membrane 6. Intracellular Compartments I. Nucleus, Nucleolus and Chromosomes 7. Intracellular Compartments 2. The Mitochondrion 8. Intracellular Compartments 3. The Plastids 9. Intracellular Compartments 3. Endoplasmic Reticulum (ER), Ribosome, 10. Cytoskeleton 11. Cell Division 12. Molecular Basis of Cell Cycle GENETICS 1. Genetics : An Overview 2. Mendels' Laws of Inheritance 3. Lethality and Interaction of Genes 4. Quantitative Inheritance 5. Multiple Alleles (Based on Classical Concept of Allelomorphism) 6. Physical Basis of Heredity (Chromosome Theory of Heredity) 7. Linkage and Crossing Over 8. Sex Linked, Sex Influenced and Sex Limited Traits 9. Sex Determination, Sex Differentiation, Dosage Compensation and Genetic Imprinting 10. Maternal Effects, Cytoplasmic Inheritance and Organellar Genetics 11. Structural Changes in Chromosomes 12. Numerical Changes in Chromosomes 13. Mutations I. Morphological Level (Including Lethal Mutations) 14. Mutations 2. Biochemical Mutations (Biochemical and Microbial Genetics) 15. Fine Structure of Gene A New Concept of Allelomorphism 16. Cell Division, Sexuality and Recombination in Bacteria and Viruses 17. Plasmids, IS Elements, Transposons and Retroelements 18. Human Genetics MOLECULAR BIOLOGY 19. Structure and Synthesis of Nucleic Acids 20. Structure and Synthesis of Proteins 2l. Regulation of Protein Synthesis 22. Genetic Code, Overlaping Genes and Split Genes 23. Recombinant DNA, PCR and DNA Chips / Microarrays 24. Synthesis, Isolation and Sequencing of Genes.

Catalogs of Courses

Molecular Basis of Heredity . ( 5 ) Three 1 - hour lectures and two discussion
sections per week . Prerequisite : Chemistry 8A - 8B ; Biology 1 A - 1B . An
introduction to the molecular basis of the structure and function of the hereditary
substance ...

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Author: University of California, Berkeley

Publisher:

ISBN: UCLA:L0077230514

Category:

Page:

View: 793

Includes general and summer catalogs issued between 1878/1879 and 1995/1997.

The Molecular Basis of Mutation

Benzer , S . , The elementary units of heredity , in The Chemical Basis of Heredity
, edited by W . D . McElroy and B . Glass , pp . 70 - 93 , The Johns Hopkins Press ,
Baltimore , 1957 . Benzer , S . , On the topology of the genetic fine structure ...

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Author: John W. Drake

Publisher:

ISBN: MINN:31951P005513582

Category: Microbial genetics

Page: 273

View: 545

Prospects for a molecular description of mutation; Why bacteriophages?; Bacteriophage genetics: first principles; Genetic mapping and the dissection of the gene; Mutation rates; Collecting mutants: procedures and precautions; Mutations in viruses; The taxonomy of mutational lesions; The origin and properties of macrolesions; Transitions; Transversions; Frameshift mutations; Chemical mutagenesis: Radiation mutagenesis; Spontaneous mutation; Mutational heterozygotes; Suppression; Complementation and polarity; Pseudomutation.

Molecular Genetics

These minute changes were called point mutations . Only a few geneticists who
possessed better knowledge of the molecular basis of heredity suggested that
modification of the chemical structure of the genetic material might be expressed
as ...

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Author: A. Gib DeBusk

Publisher:

ISBN: UCAL:B4283529

Category: Cytogenetics

Page: 134

View: 106

The Genetic Basis of Common Diseases

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Author: Lowell King

Publisher: Oxford University Press, USA

ISBN: UOM:39015029162701

Category: Medical

Page: 978

View: 219

Here is a unique and comprehensive resource for human geneticists and physicians concerned with the genetic causes of diseases routinely seen in research, clinical practice, and genetic counseling. Each of the chapters covers a particular disease, describes the genetic factors involved, and define the relevant biochemical, immunological, and physiological markers. The expert, widely known contributors also detail clinical applications, with advice on how the genetic data can be used to evaluate individuals and families, interpret diagnostic texts, and manage the disease.

Research Grants Index

tt ** PO1HD - 08536-01 0005 Cellular mechanisms in mental RO1HD - 00193-20
Mechanisms of genetic control of ... DEFICIENCY RO1AM - 13359-07 Molecular
basis , genetics of glycogen RO1HD - 06355-04 Etiology of hypoglycemia in ...

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Author: National Institutes of Health (U.S.). Division of Research Grants

Publisher:

ISBN: UOM:39015072175394

Category: Medicine

Page:

View: 801

Problems of Radiation Genetics

Study of the problems of radiation genetics cannot be separated from
investigations on the chemical and physical bases of heredity . It is only since the
discovery of the molecular basis of heredity , and the biological characteristics of
this ...

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Author: Nikolaĭ Petrovich Dubinin

Publisher: Edinburgh : Oliver & Boyd

ISBN: UOM:39015004382217

Category: Genetics

Page: 445

View: 369

Concepts in Biology

DNA AND RNA : The Molecular Basis of Heredity SA ind top other the there you
way to their to be CHAPTER OUTLINE The Structure of DNA and RNA The
Molecular Structure of DNA The Main Idea : The Central Dogma DNA Replication
DNA ...

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Author: Eldon D. Enger

Publisher: McGraw-Hill Science, Engineering & Mathematics

ISBN: 0697272052

Category: Science

Page: 458

View: 525

Concepts in Biology is a short, student-friendly text organized in a traditional manner. It has very little botany and presents a human-oriented approach to the animal unit. Professors and students appreciate the low cost of this title, and that it is written for students who are not biology majors.

Essentials of Genetics

In Chapter 3 , we will return to a thorough analysis of Mendel's findings , which to
this day serve as the foundation of ... It is useful to give a brief overview of the
molecular basis for genetic function that serves as the underpinnings of the more
 ...

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Author: William S. Klug

Publisher: Benjamin Cummings

ISBN: STANFORD:36105110403982

Category: Science

Page: 508

View: 511

/* 9126D-2, KLUG/CUMMINGS, Essentials of Genetics, 4E */ Presents a succinct overview of the discipline, with balanced coverage of both classical and modern genetics. Known for their clear writing style, emphasis on concepts, visual art program, and thoughtful coverage of all areas of genetics, the authors capture interest with up-to-date coverage of cutting edge topics and research. This book will help readers connect the science of genetics to the issues of today through interesting and thought provoking applications. Revision features 3 new chapters: Chapter 5, Sex Determination and Sex Chromosomes, Chapter 18, Genomics and Proteomics, and Chapter 24, Conservation Genetics—Genenomics and Proteomics put this book at the cutting edge of a rapidly moving field. The Conservation Genetics chapter is the first really new chapter that has appeared in any genetics book over the past decade. The Population Genetics and Evolutionary Genetics chapters are updated and significantly enriched by Jon Herron (co-author of Evolutionary Analysis, 2/e). The Technology and Society Essays include numerous revisions and several new topics—Genetically Modified Foods is addressed with a new essay in Chapter 1; new essay in Chapter 18 addresses Gene Therapy in the context of Genomics; there are two short boxes that represent “molecular snippets” in the transmission genetic chapters (3 and 5); and new section on molecular genetics in Chapter 1. Two biotechnology chapters cover technologies and analysis, and applications and ethics. Human behavior genetics includes recent findings on genes controlling manic depression (Chapter 20). Up-to-date coverage of contemporary topics includes ethical questions raised by genetic testing and the human genome project. It will appeal to evolutionarily-oriented professionals in the biological sciences, zoology, agriculture, and health science fields.

Sci tech Book Profiles

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Author:

Publisher:

ISBN: STANFORD:36105117253042

Category: Science

Page:

View: 693

Includes title page, table of contents, list of contributors, preface and all indexes of each book.

Molecular Biology

Uses wit, humour and a lively writing style to introduce the subject to anyone interested in the nitty-gritty of the genetic revolution.

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Author: David P. Clark

Publisher:

ISBN: STANFORD:36105019304810

Category: Alm

Page: 470

View: 446

Uses wit, humour and a lively writing style to introduce the subject to anyone interested in the nitty-gritty of the genetic revolution.