Veterinary Pharmacology and Therapeutics

Provides current, detailed information on using drug therapies in all major domestic animal species Organized logically by drug class and treatment indication, with exhaustive information on the rational use of drugs in veterinary medicine ...


Author: Jim E. Riviere

Publisher: John Wiley & Sons

ISBN: 9781118855829

Category: Medical

Page: 1552

View: 484

Veterinary Pharmacology and Therapeutics, Tenth Edition is a fully updated and revised version of the gold-standard reference on the use of drug therapy in all major veterinary species. Provides current, detailed information on using drug therapies in all major domestic animal species Organized logically by drug class and treatment indication, with exhaustive information on the rational use of drugs in veterinary medicine Includes extensive tables of pharmacokinetic data, products available, and dosage regimens Adds new chapters on pharmaceutics, ophthalmic pharmacology, food animal pharmacology, and aquatic animal pharmacology Includes access to a companion website with the figures from the book in PowerPoint

Textbook of Therapeutics

The contributors to this volume deliver information on latest drug treatments and therapeutic approaches for a wide range of diseases and conditions.


Author: Richard A. Helms

Publisher: Lippincott Williams & Wilkins

ISBN: 9780781757348

Category: Medical

Page: 2780

View: 240

The contributors to this volume deliver information on latest drug treatments and therapeutic approaches for a wide range of diseases and conditions. Coverage includes discussion of racial, ethnic, and gender differences in response to drugs and to biotechnical, pediatric and neonatal therapies.

Ocular Therapeutics Handbook

The Treatment No therapeutic intervention has been proven effective , but avoidance of the identified epigenetic triggers ( smoking , alcohol ) is highly recommended in those at risk . Lowvision aids are sometimes helpful .


Author: Bruce E. Onofrey

Publisher: Lippincott Williams & Wilkins

ISBN: 0781748925

Category: Medical

Page: 724

View: 757

This compact, portable, and user-friendly clinical manual is geared to the needs of all health care professionals who treat ocular disorders. Organized and designed for rapid reference, the book is packed with information on the entire spectrum of ocular disorders and their treatment. This Second Edition is thoroughly updated, greatly expanded in scope, and includes ICD-9 codes. The book begins with a Quick Reference Section where clinicians can find vital facts about ocular microbiology, laboratory tests, ocular side effects of systemic medications, and pharmaceutical agents used in eye care. The second section contains succinct, well-organized monographs on over 150 disorders.

Development of Antibody Based Therapeutics

This volume provides a comprehensive review of the topics critical for establishing successful translational strategies for the development of antibody-based therapeutics.


Author: Mohammad A. Tabrizi

Publisher: Springer Science & Business Media

ISBN: 9781441959553

Category: Medical

Page: 426

View: 238

Translational strategies for development of antibody-based therapeutics should allow understanding of the relationship between the ‘unit dose’ and ‘unit effect’ with respect to both beneficial and deleterious effects from early stages of development. The flow of information from later to earlier stages of development should provide opportunities to facilitate selection of more effective novel and next-generation drug candidates. Selection and evaluation of relevant biomarkers in early preclinical development in "relevant" animal models should allow for identifying potential risks to humans and establishing safe First-In-Human (FIH) dosing strategies. Hence, integration of knowledge with respect to target antigen properties such as antigen distribution, expression profile, kinetic properties, target pharmacology, antigen isoforms and pharmacological redundancy in health and disease, as well as antibody design criteria, such as antibody isotype, affinity, PK/PD and safety is a critical necessity for the design of effective translational strategies. Additionally, these factors will further offer critical differentiating characteristics for next-generation antibodies, and novel technologies prove instrumental in generation of biosuperior antibody candidates for market entry. This book will examine many important considerations necessary for the design of effective translational strategies during the development of antibody-based therapeutics.

Protein Therapeutics 2 Volume Set

As discussed in detail in the sections above, the majority of innate receptors expressed by DC facilitate endocytosis, and result in more efficient presentation of peptides to T cells by delivering protein therapeutics to the endosomal ...


Author: Tristan Vaughan

Publisher: John Wiley & Sons

ISBN: 9783527699148

Category: Medical

Page: 480

View: 317

In this practice-oriented two volume handbook, professionals from some of the largest biopharmaceutical companies and top academic researchers address the key concepts and challenges in the development of protein pharmaceuticals for medicinal chemists and drug developers of all trades. Following an introduction tracing the rapid development of the protein therapeutics market over the last decade, all currently used therapeutic protein scaffolds are surveyed, from human and non-human antibodies to antibody mimetics, bispecific antibodies and antibody-drug conjugates. This ready reference then goes on to review other key aspects such as pharmacokinetics, safety and immunogenicity, manufacture, formulation and delivery. The handbook then takes a look at current key clinical applications for protein therapeutics, from respiratory and inflammation to oncology and immune-oncology, infectious diseases and rescue therapy. Finally, several exciting prospects for the future of protein therapeutics are highlighted and discussed.

Samuels s Manual of Neurologic Therapeutics

In fact, neurology has long been known as a discipline with elegantly precise and specific diagnostic capabilities but little or no therapeutic potentiality. Further, many surgeons, pediatricians, and internists have traditionally ...


Author: Martin A. Samuels

Publisher: Lippincott Williams & Wilkins

ISBN: 9781605475752

Category: Medical

Page: 607

View: 770

"An essential resource for neurologists and neurology residents, Samuel's Manual of Neurologic Therapeutics provides concise, evidence-based guidance for diagnosing and treating neurologic disorders. This edition adds Allan H. Ropper, one of the world's leading neurologists, as co-editor."--BOOK JACKET.

Clinical Pharmacy and Therapeutics E Book

It will also be of great use to anyone doing a course in pharmacotherapy. This book will always be of use to you throughout your studentship or when practising after graduation.


Author: Cate Whittlesea

Publisher: Elsevier Health Sciences

ISBN: 9780702070105

Category: Medical

Page: 992

View: 932

‘This new edition of Clinical Pharmacy and Therapeutics was really very helpful when I was doing an MSc course in Advancing Pharmacy Practice and it was really very helpful in all the clinical diseases I have to read for my PBL. I also used it as one of my most reliable reference books for the in-course simulation ward rounds and other clinical case studies. It is a great book to have as a practising clinical or hospital pharmacist or even community pharmacist. It will also be of great use to anyone doing a course in pharmacotherapy. This book will always be of use to you throughout your studentship or when practising after graduation. It is also more portable than most other pharmacotherapy textbooks with the same amount of information.’ Now in its sixth edition, this best-selling, multi-disciplinary textbook continues to draw on the skills of pharmacists, clinicians and nurses to present optimal drug regimens. The authors integrate an understanding of the disease processes with an appreciation of the pathophysiological processes, clinical pharmacy and the evidence base. Each chapter is co-written by a pharmacist and a clinician, and each chapter begins with key points and ends with cases to test understanding. The sixth edition is now on StudentConsult for the first time, giving online access to the full text. Key points boxes at the beginning of each chapter Case-study boxes throughout the chapters Each chapter co-written by a pharmacist and a clinician In-depth treatment of therapeutics to support pharmaceutical prescribing Logical order and format: key points, epidemiology, aetiology, disease, clinical manifestations, investigations and treatment, drugs used in treatment. Dosage reference sources given where appropriate, along with useful websites and further reading for each chapter. New co-editor, Karen Hodson Over 10 new authors Now in 4-colour On StudentConsult for the first time New chapter on Dementia Many new and revised illustrations Chapters revised to include advances in therapeutics and changes to dose regimens and licensed indications Updated case studies

Molecular Therapeutics

However, for many diseases we do not need molecular therapeutics. In these cases we use conventional methods to treat the patient. We do not achieve a cure but we improve the life of the patient. If a disease causes a reaction to a ...


Author: Pamela Greenwell

Publisher: John Wiley & Sons

ISBN: 0470725141

Category: Science

Page: 264

View: 254

"This book should be useful to lecturers who teach senior undergraduates, graduate students, and students in the biomedical sciences in general. More globally, Greenwell and McCulley's book should encourage academicians of any stripe who for some time have been honing their lectures in a niche subject area to turn their courses into textbooks." –Biochemistry and Molecular Biology Education Molecular therapeutics refers to the developments in molecular biology that are focused on treating disease with new molecular-based drugs. By taking advantage of recent advances and increased understanding in the field of human genetics, this book provides essential background knowledge and key literature on a broad range of novel approaches and disciplines. These include making recombinant proteins, xenotransplantation gene therapy and therapeutic cloning. Molecular Therapeutics: 21st Century Medicine describes the techniques - including their associated benefits, problems, pitfalls - and discusses their applicability with respect to treating microbial, inherited, multifactoral and acquired diseases. The book also pays specific attention to the ethical issues associated with this new field. Cutting-edge topics and clinically relevant materials engage and maintain student interest Self-assessment questions are included throughout the book Features an additional web site, with a web forum, regular updates and PowerPoint slides of figures from the book Molecular Therapeutics: 21st Century Medicine is a comprehensive, accessible and engaging guide to the rapidly developing field of molecular therapeutics. It is essential reading for all students in this area of research and also of interest for health professionals involved in these novel therapies.

Anti Aging Therapeutics Volume XVII

The content presented in the Anti-Aging Therapeutics, volume 17 is for educational purposes only and is specifically designed for those with a health, medical, or biotechnological education or professional experience.


Author: A4M American Academy of Anti-Aging Medicine

Publisher: A4M American Academy of Anti-Aging Medicine

ISBN: 9781934715192

Category: Medical

Page: 225

View: 583

Proceedings of the Twenty-Second World Congress on Anti-Aging Medicine & Regenerative Biomedical Technologies, sponsored by the American Academy of Anti-Aging Medicine (A4M).

Safety and Efficacy of Gene Based Therapeutics for Inherited Disorders

However, it is now believed that siRNA therapeutics are unlikely to be genotoxic based on their properties and the results of oligonucleotides tested so far. However, genotoxicity testing is recommended for oligonucleotides that contain ...


Author: Nicola Brunetti-Pierri

Publisher: Springer

ISBN: 9783319534572

Category: Medical

Page: 220

View: 557

In this book, leading international experts analyze state-of-the-art advances in gene transfer vectors for applications in inherited disorders and also examine the toxicity profiles of these methods. The authors discuss the strengths and weaknesses of available vectors in the clinical setting, and specifically focus on the challenges and possible solutions that researchers are testing in order to improve the safety of gene therapy for genetic diseases. This comprehensive and authoritative overview of vector development is a necessary text for researchers, toxicologists, pharmacologists, molecular biologists, physicians, and students in these fields.